Monthly Archives:2018年2月
Antithrombotic therapy duration after coronary stenting: finding the sweet-spot with a novel clinical risk score
Coronary atherosclerosis is still the principal cause of morbidity and mortality in western countries, by inducing ischemia or infarction of the myocardium. Percutaneous treatment of atherosclerotic lesions is nowadays the most common form of treatment of such
Are moths as old as dinos?
The larvae of moths have eight pairs of legs. The moth family Geometridae is specific in that their larvae have five pairs of legs and move by looping: “looper moths”. One of geometrid subfamilies, Geometrinae, has green
How does phenobarbital, a therapeutic sedative, activate a nuclear receptor through phosphorylation?
Steroid hormones activate a family of nuclear proteins called nuclear receptors to regulate every aspect of human physiology, reproduction, development, differentiation, metabolism and immunity. A nuclear receptor molecule is comprised of two major structural domains; DNA-binding (DBD)
mRNA decay activity in neurons regulates survival of worms at high temperatures
The ability of an organism to quickly alter or fine-tune its gene expression profile as a response to unfavorable and stressful conditions is a vital trait that can determine its chances of growth and survival in unstable
23rd International Conference on Pharmaceutical Biotechnology. Rome, Italy. December 10-11, 2018
Conference Series LLC is a renowned organization that organizes highly notable conferences throughout the globe. Currently we are bringing forth 23rd International Conference on Pharmaceutical Biotechnology (Pharma Biotech 2018) scheduled to be held during December 10-11, 2018
Sole Pheromones: “What we have here is a failure to communicate”?
Pheromones are an important, but understudied, facet of reproduction in many animals. What we know about pheromones in fish mostly comes from freshwater species. However, many economically important species are marine. One such is the Senegalese sole
Transcription modulation in Xanthomonas citri subsp. citri
Xanthomonas citri subsp. citri (X. citri) is a Gram-negative bacterium and the etiological agent of citrus canker, a severe disease that affects all the commercially important citrus varieties with worldwide distribution. The best method to control the
What else can a robot do? Reducing the use of hormone in the dairy industry!
Contrary to an increase in milk yield, dairy cows exhibit weaker and shorter heat signs than ever before. It causes a stockman hard to observe the estrus signs. Thus, efforts to promote reproduction efficiency have focused on
Does non-clinical maternal depression have a lasting effect on mother-infant interactions?
The special emotional bond that forms between a mother and her infant appears very early in life. Integral to this relationship is the infant’s ability to be able to detect contingencies between his or her own behavior
The T cell IFT20 interactome: new insights into immune synapse assembly regulation by the IFT system
T lymphocytes are key cellular components of the immune system that are essential for the elimination of viral, bacterial and parasitic infections as well as of malignant cells. T cell activation is initiated following recognition of pathogen-
Characteristics of children with familial and idiopathic dilated cardiomyopathy
Dilated Cardiomyopathy (DCM) is a disease characterized by weakening of the heart muscle that becomes dilated and unable to pump blood efficiently. DCM is diagnosed in 0.57 of 100,000 children per year in North America and has
Towards better tissue regeneration: Improved vessel growth using synthetic polymers
The formation of vascular network is crucial for development and function of most of the tissues due to oxygen and nutrients supply and removal of toxic metabolites. In case of an injury such as bone or soft
Toscana virus circulation in central and southern Italy
Sandfly fever viruses are widely distributed in the Mediterranean basin, where they are transmitted by the bite of sandflies in the breeding season. The most common viruses associated with human infections are sandfly fever Naples virus, sandfly
Metal-organic framework with dangling sulfonate groups for enhanced proton conductivity
Metal-organic frameworks (MOFs) provide a versatile platform for tuning the chemical functionality of pore surfaces and thus have attracted an increasing amount of attention for applications in gas storage, molecular separation, sensing, and catalysis. In contrast to
Vitellogenesis: not only in the liver and not only in females
Vitellogenin (VTG) is an estrogen-dependent, females-specific yolk precursor protein naturally synthesized during the reproductive period in the liver of oviparous vertebrates. Released in blood, VTG is taken from the growing oocytes by micropinocytosis and used as nourishment
Expression, purification and functionality of bioactive recombinant human vascular endothelial growth factor VEGF165 in E. coli
Angiogenesis, the growth of blood vessel from the existing vasculature, depends on the expression of various growth factors but Vascular Endothelial Growth factor (VEGF) ranks as the key inducer and the central mediator that promotes vascular permeability.
Treating white spots of vitiligo
Skin color is such a critical part of our sense of who we are. Skin color varies from dark brown to pale white. Our skin color defines our “tribe”, that group of people with whom we identify
Dual functionality of a graft starch flocculant: flocculation and antibacterial performance in water treatment
Water treatment agents, including coagulants / flocculants, bacteriostatic / bactericidal agents, scale inhibitors, etc., play very important roles in the field of water treatment. However, traditional water treatment agents usually possess single functionality only, causing a wide
Bioelectro-Fenton: a sustainable process for the removal of pharmaceuticals residues from water
Water scarcity is one of the main environmental issues humanity is facing. This situation is aggravated by the constant release of refractory contaminants into water reservoirs due to the incessant growth of the industrial activity. These so
How do cats avoid small obstacles during walking?
Avoiding obstacles obstructing a walkway is a usual, but not a trivial motor task. A lot of work had been done so far to elucidate how biped humans solve this task, but only a few efforts were
