Monthly Archives:2016年12月
Management of apathy in the long-term care setting
Management of apathy is a very important issue in the long-term care because many residents with neurodegenerative disorders suffer from this syndrome. In Alzheimer’s disease, apathy is the most common behavioral syndrome and may occur already in
Understanding Schwann cells: new insights into the developing peripheral nervous system
Our study focuses on signals that control the development and function of Schwann cells, which are glial cells that reside in the peripheral nervous system (PNS). Schwann cells sort axons, surround the axons and form a myelin
Feeding bacteria inhabiting oil reservoirs may enhance oil production
Bacteria live in oil reservoirs and eat the oil. Some of them are known to produce surface active molecules (biosurfactants), which act as detergents. Biosurfactants may help produce more oil through breaking globs of oil trapped in
Functional transcranial Doppler ultrasonography in the study of central sensitization to pain in fibromyalgia
Fibromyalgia syndrome ( FMS ) is a chronic disease characterized by persistent and widespread musculoskeletal pain in addition to symptoms like depression, fatigue, sleep disturbance and impaired mental performance. The etiology and pathophysiology of FMS remain to
A new representation of the nervous system: the hypermatrix
It is a big challenge to develop the most appropriate mathematical model to describe the electrical activity of different groups of neurons. There are more neurons in the nervous system (about 86 billion) than we have seconds
Ultrastructural and molecular characterization of Glugea serranus, a microsporidian parasite infecting the blacktail comber
Microsporidians ( phylum Microsporidia Balbiani, 1882 ) are unicellular organisms that develop as obligatory intracellular parasites in different animal hosts, particularly in arthropods and fish. To date, about 187 genera have been described, 21 of which parasitize
LEP patients and call light communication
In hospitals across the United States, call light systems are used for patients to communicate directly with their health care providers. Communicating needs with English-speaking health care providers is difficult for limited English proficiency (LEP) patients who
Family, cholesterol and the genes from the ground up or why screening matters
In 1913, the “cholesterol theory” of atherogenesis was proposed. In the 1930s a genetic disorder, familial hypercholesterolemia (FH), which is associated with elevated levels of low-density lipoprotein (LDL) cholesterol and high risk of heart attack at an
Towards safer prescribing of benzodiazepines and z-drugs
Benzodiazepines and z-drugs are medicines used to treat things like insomnia, anxiety and some types of pain. Guidelines recommend that they should only be taken in the short-term, but research shows that patients are taking them long-term.
Catch the metabolomic fingerprint of a complex natural product and predict its quality!
This is the first work published so far, that shows the application of a comprehensive metabolomic fingerprint analysis to assure the production’s quality of complex natural products, especially those based on medicinal plants. Natural products as medicinal
Toxicity of graphene in lung alveolar epithelial cells
Graphene is a fascinating nanomaterial that has garnered significant scientific interest because of its unique properties such as superior thermal and electrical conductivity, high mechanical strength and unique optical properties. Due to this reason graphene has numerous
Bioactive hollow nanofiber-based leaves can convert CO2 to methanol under irradiation of visible light
Using limitless solar energy to produce artificial energy and chemical fuels from CO2 provide one of the most promising strategy overcoming the depletion of mineral resources on earth and over emissions of carbon dioxide. In nature, such
The risk of childhood eczema is associated with immune molecules in mothers breast milk
Maternal breast milk is the main source of nutrition during early life, which is a critical period for immune development of the child. Breast milk contains bioactive enzymes, hormones, growth factors and immune modulating factors, which are
Use of mental health services provides long term benefits to adolescent witness of violence in community
Violent victimization is known to negatively affect healthy progression of adolescents’ development. Thus far, we know it is linked to multiple adverse health risk behaviors such juvenile delinquency, increased levels of violent behavior and weapon use, increased
Non-invasive whole-body imaging of fibrosis: is it feasible?
Fibrosis is a chronic, life-shortening disease that can occur either as a consequence of genetic defects or in response to inflammation or damage. Such body systems as respiratory, gastrointestinal, musculoskeletal, genitourinary, and reproductive can be affected. Fibrosis
滥交以多巴胺受体的药物ligands
Dopamine, often referred as “the happiness hormone”, is one of the most prominent messenger molecules in the human brain. It is a precursor of noradrenaline and adrenaline, which are neurotransmitters as well. Most people heard about dopamine
Hyper IgM syndrome in North America: a rare disease of a critical step in the immune response pathway
Hyper IgM (HIGM) syndromes are a group of rare genetic disorders leading to ineffective immune responses. People with this immune defect are usually diagnosed in early childhood due to frequent infections. Most of these are common but
Downside of graphene – a miracle material
Any engineered nanomaterials should undergo thorough investigation on risk and health hazards imposed by them before available in the market for consumption. Graphene, a 2D carbon based material with hexagonal lattice structure along with its inherent physicochemical
Migration and perinatal mental health
There are currently an estimated 1 billion migrants globally, with trends increasing dramatically. Migrants have higher rates of physical and mental illness than their non-migrant counterparts due to multiple stressors experienced before, during and after migration (Fig.
Eye opener: the gate for immune cells entering the injured eye
Disease or injury to the retina or optic nerve is one of the main causes of blindness worldwide. As such, major research efforts have been invested in finding ways to protect the neuronal cells of the retina
