Daily Archives:February 22, 2016
With a little help from friends: how plastids aid the ER to deal with misfolded proteins
Almost a third of all proteins in eukaryotic cells are synthesized and folded in the endoplasmic reticulum (ER) before being secreted and redistributed to other organelles, such as the Golgi apparatus, lysosomes, and the plasma membrane. To
Heart disease in cancer patients (onco-cardiology / cardio-oncology)
In the United States, heart disease and cancer have been the 2 leading causes of death from 1935 through 2013. In 2010, both diseases accounted for almost half of all deaths in the U.S. Notwithstanding, much success
Plasmid-mediated carbapenem and colistin resistance in E. coli – toward a dead end
The increasing trend in antibiotic resistance continues to threaten global health. Presently, multidrug resistance (MDR) in gram-negative rods is frequently observed not only with the occurrence of extended-spectrum ß – lactamase but also with producers of enzymes
持久impa感官剥夺在生命早期cts
What happens to a brain area when it is underutilized when a person or animal is growing up? Does this kind of deprivation of experiences lead to negative effects for brain development? For a long time, the
Parkinson disease and duodenal levodopa infusion: why patients withdraw the treatment?
Parkinson disease is a chronic and progressive movement disorder associated to degeneration of neurons in the brain, particularly in a region called substantia nigra. These neurons produce dopamine, a neural transmitter that is involved in the control
交通噪音增加肥胖的风险吗?
There is an association between road traffic noise and the risk of obesity among people who are particularly sensitive to noise, according to a study from the Norwegian Institute of Public Health. Previously, a Swedish study reported
Identification of drusen characteristics in age-related macular degeneration
In this study, we investigated the morphologic characteristics of drusen in order to determine their composition, using an in-vivo technique, the optical coherence tomography (OCT). The development of drusen is an important characteristic of age-related macular degeneration
Making drug discovery more efficient: predicting drug side effects in early screening efforts
Drug research and development is a complex and expensive process that begins with initial screening steps of candidate chemical compounds. Compounds that appear to have the desired potency against a specific cellular target or pathway are further
An algal infection (protothecosis) in a cat
This case report describes a cat with inflammation caused by an infection with a particular type of algae named Prototheca. The evoked clinical disease is called protothecosis. Prototheca species and their occurrence in the environment. Prototheca species
In silico prediction of ebolavirus RNA polymerase inhibition
A virus at work: Let us assume that you are a virus that just infected a cell (the HOST CELL) of an individual (the PATIENT). What is your vicious objective? You want to make copies of yourself
