Daily Archives:February 25, 2016

HDL cholesterol: sometimes more is not necessarily better

Lipoproteins are complex particles that are responsible for transporting the water insoluble molecule, cholesterol, through the blood stream. Cholesterol is transported from the liver to peripheral tissues. Excess cholesterol in low-density lipoprotein (LDL) is deposited in the

A synaptic receptor with a dual personality

Learning and storage of information in the brain at the cellular level involves dynamic modification of synapses, the place where information passes from a neuron to another. The efficacy of this transmission of information changes and depends

TGFbeta signalopathies as a paradigm for translation medicine

Marfan syndrome (MFS) is a disorder that affects different organ systems, such as the heart, aorta, eyes and the skeleton. Typically MFS patients present with tall stature, hands with long fingers, chest deformity. One of its most

Parkinson’s alpha-synuclein assembles in the disease prone stable dimers

The self – assembly of proteins into amyloid – type aggregates is a widespread phenomenon associated with many neurodegenerative diseases, including Parkinson’s disease (PD). According to the current model for PD, the aggregation of alpha-Synuclein (α-Syn) and

Importance of updating prognostic predictions: an example from breast cancer

Today prognostic prediction models are an integral part of clinical practice in many fields. They are typically used to access the risk of an event in the future after a well-defined starting point, for instance the risk

Understanding stability in functional nanoparticle inks

The past decade has seen an explosion of interest in 3-D printing. While many applications of 3-D printing use curable polymers to construct macroscopic scale objects (think printing of toys, jewelry, and architectural models), one of the

Heat-alkalinity-time pasteurization can efficiently inactivate PEDV in porcine plasma

Emergence of porcine epidemic diarrhea virus (PEDV) in North America and Asia resulted in massive losses to the pork industry. The virus is spread by the fecal-oral route and infection can cause acute diarrhea, dehydration and vomiting

Sexual dimorphism in pituitary prolactin tumors

The pituitary is located in the middle of the skull base, under the brain. This gland weight less than 1 g but its five cell types control growth, lactation and hormonal production by the thyroid, adrenals and

European Pharma Summit 2016

Organizer: GTCbio Start date: May 11th, 2016 End date: May 13th, 2016 We invite you to attend the European Pharma Summit 2016, which will take place on May 11-13, 2016 in Berlin, Germany. This event seeks to