Daily Archives:October 8, 2019

New psychoactive substances: metabolites of synthetic cathinones induce cytotoxicity in human neuronal cells

New psychoactive substances. AoS

Recently, a large number of novel psychoactive substances (NPSs) have appeared on the European market. Their growing diffusion has become matter of worldwide concern and alarm for public health authorities, legislators, and clinical health specialists. They are

The RAS mRNA G-quadruplex: making undruggable cancer targets druggable

The RAS mRNA G-quadruplex. AoS

In many cancers, RAS proteins are constitutively activated by their oncogenic mutations or activation of their upstream molecules. RAS proteins play a central role in cancer cell malignancy, and drugs that target RAS are therefore believed to