Daily Archives:October 14, 2015
Methylation profile of DMPK gene in myotonic dystrophy type 1 (DM1)
Myotonic dystrophy type 1 (DM1, Steinert’s disease), is the most common muscular dystrophy in adult life, characterized by myotonia (prolonged muscle contractions), muscle weakness, cataract, cardiac disease, gastrointestinal abnormalities, and central nervous system dysfunction. The clinical spectrum
Natural history of spinocerebellar ataxias
The spinocerebellar ataxias (SCAs) are autosomal, dominantly inherited progressive ataxia disorders. More than 35 genetically different SCAs have been defined. The most common, SCA1, SCA2, SCA3, and SCA6, which together affect more than half of all families
Bioinspired photocatalyzed Alkyl/Aryl thiosulfate transformation for drug modification
Aiming to conserve energy and reduce emissions, chemists have been trying to mimic the complex photosynthetic process of plants in relatively simple chemical ways, such as photocatalyzed reduction of carbon dioxide and solar-driven splitting of water into
A tutorial on randomized study designs for lifestyle interventions
Unhealthy lifestyle behaviours such as an unhealthy diet, excessive energy intake, smoking, excessive alcohol use, physical inactivity and poor stress-coping behaviour can act as causal factors in the pathway of many diseases. There are various types of
