Tag Archives:vascular disease
Angiotensin II actions on distal regulatory elements promote vascular dysfunction and hypertension
Cardiovascular diseases such as hypertension (high blood pressure) and atherosclerosis (blocked blood vessels) lead to heart attacks and strokes, and are highly prevalent worldwide. Furthermore, these complications are significantly accelerated in patients with diabetes. Angiotensin II (AngII)
Is caveolin-1 depletion the key to endothelial cell phenotypic switching in inflammatory vascular disease?
Endothelial cells (ECs) function as the central regulators of blood – tissue communication, controlling the exchange of solutes and immune cells between the vascular and extravascular compartments. In healthy lungs, quiescent ECs express high levels of caveolin-1
