Tag Archives:pain
Dysfunction of cellular analgesic control in neuropathic pain
Neuropathic pain in small-fiber neuropathy was traditionally considered a consequence of injury to nociceptors and sensitization. An alternative view has also been put forward: there may be a loss of the neuronal analgesic control system, paralleling the
Inflammation alters brain function and pain processing centrally
In the last couple of years, some fascinating abilities of the immune system have emerged: The immune system is tightly interconnected with the nervous system, and can directly affect how the brain functions, and how a person
Abdominal wall schwannoma
A 62-year-old woman was admitted to our institution for the surgical evaluation of a mass in the right iliac fossa causing an enduring abdominal pain. The patient presented with the following comorbidities: visceral class I obesity (BMI
Stress must not be confused with pain
Our article “Stress is not pain” was a critique on a study by Elwood & Adams who exposed crabs to electric shocks and concluded that their study ‘. . .fulfils the criteria expected of a pain experience’.
GlyT2 inhibitors: Getting the balance right
In the central nervous system, signals are sent through brain pathways using neurotransmitters, the chemical messengers of our brain. The strength and duration of these messages are governed by the concentration of neurotransmitters in the synapses between
Older Australians in nursing homes have limited access to complementary medicines for pain relief
In Australia and elsewhere, older people living in the community use complementary medicines (CM) to manage the symptoms of chronic illnesses, especially pain, and to supplement ‘conventional’ medical treatments for the same conditions. The bulk of CM
Benefits of aging?
Does pain increase or decrease with age, and if so, what causes the change? A factor we considered is that sensitivity to pain could be altered by an age-related loss of neurons involved in regulation of affective/emotional
Do you have pain on the lateral side of your knee (often diagnosed as iliotibial Band Syndrome)?
Runners, bicyclists, and many other active individuals who experience pain along the lateral side of their knee joint are often diagnosed as having iliotibial band syndrome or iliotibial band friction syndrome. This problem is attributed to a
Glucosamine reduces the need for pain medications in osteoarthritis, but the correct formulation is essential
For osteoarthritis, drugs that can delay disease progression have the potential to reduce the need for additional pain medications. But be careful which drug you chose: this effect is only shown with the prescription patented crystalline glucosamine
Extended VATS lobectomy
A lobectomy is the standard operation for removal of a lung cancer. Traditionally, it is performed through a large incision (approximately 15 cm or 6 inches) at the side of the chest. This incision, termed a thoracotomy,
PACAP expression induced in neuropathic pain is controlled by a splicing of REST/NRSF
Neuropathic pain (NP) is caused by the damage of the nervous system and one of the most common types of intractable pain. It is often severe, persistent, and refractory to available therapies. Although various analgesic has been
Time for a new understanding of chest pain
Most people who present to hospitals with pain in the chest have nothing wrong with their hearts. A small proportion have another physical problem such as acid reflux from the stomach but most have health anxiety or
一个简单的方法Study of Acid Sensing Ion Channels (ASICs) by fluorescence
The presence of severe acidosis has been demonstrated to be associated to several pathological conditions, such as multiple sclerosis, brain trauma, spinal cord injury and epilepsy as well as in inflammatory pain, to cite the most relevant.
Rare and uncommon cancers
A rare cancer is one that occurs less than 6 times in 100,000 people and an uncommon cancer is found between 6 and 12 times in each 100,000 people. The problem with being rare is that there
Radiation therapy for nerve pain when cancer spreads to bones
One of the hallmarks of cancer is its ability to spread from the primary site of origin to other places in the body. Such secondary sites are called “metastases”. One of the commonest sites for cancer secondaries
A novel platform to measure orthodontic actions
Orthodontics is the medical specialty, where there exists the strongest link between biomechanics and treatment outcome: the application of mechanical tools and instruments to achieve tooth movement and thus correct malocclusions. However, for many clinicians this link
The role of the thalamic submedius nucleus histamine in modulation of formalin-induced orofacial pain
Pain is one of the most common and disturbing of human experiences. While it has many causes, the appreciation of painful sensation depends on the stimulation of pain receptors (nociceptors) and the conduction of the nerve impulses
A disease of younger women
Cramp or pain during menstruation is very common, but telling a young woman that this is ‘normal’ without full assessment can be wrong as this can lead to many years of unnecessary suffering. There are many conditions
How can I create more mobility in my stiff shoulder?
A stiff shoulder, or the so-called “frozen shoulder”, is a disorder characterized by progressive pain and loss of mobility of the shoulder. The annual incidences are 3 to 5% in the general population and even up to
