Monthly Archives:November 2018

Oncogenic role of CircPVT1 in head and neck squamous cell carcinoma

Circular RNAs (circRNAs) are a class of endogenous non-coding RNAs that have recently shown to behave as gene regulators in eukaryotic cells, extending our previous knowledge regarding the diversity and complexity of the transcriptome. Nowadays, circRNAs have

Nerve conduction inhibition by various antidepressants used to alleviate chronic pain

信息的疼痛的刺激the periphery is transmitted through the dorsal root to the superficial spinal dorsal horn, and then flows to the primary-sensory area of the cerebrum through the brainstem and thalamus, causing pain

New inflammatory properties of nanoparticles (NPs): NPs can alter the biology of human eosinophils

The term nanoparticles (NPs) refer to particles with a very small size ranging in the nanometer scale. One nanometer (nm) is a unit of measure corresponding to a billionth of a meter. In general, the definition of

Shedding new light on the causes and treatment of chronic unexplained stomach symptoms

Across the world, about one in six people suffer from chronic stomach symptoms, including feeling very full and uncomfortable or bloated after eating, being unable to finish a normal sized meal and experiencing after meals frequent stomach

Aflatoxin B1: a foodborne contaminant which impairs sperm quality and fertilization competence

The gradual decline in fertility of human and farm animals over the past few decades coincides with intensive industrial and agricultural development. Multiple environmental factors affect sperm function and fertility, among them are aflatoxins, poisonous byproducts of

Genomics-based selective breeding of forest trees

The selective breeding of forest trees is a long-term endeavor requiring sustained organizational and financial commitments, and follows the recurrent selection scheme with protracted repeated cycles of selection, mating and testing. This process encounters numerous challenges including

Artifacts in AFM topography images of TMD monolayers

Initially motivated by work with graphene, the broad class of two dimensional (2D) materials has generated enormous interest. Monolayers and heterostructures of transition metal dichalcogenides (TMDs) have attracted intense investigation as the long awaited 2D semiconductor analogs

Prenatal exposure to bisphenol A and phthalates may modify fetal adipokines

Bisphenol A and phthalates are widely detected in human urine, blood, breast milk, and amniotic fluid. Bisphenol A is widely used in polycarbonate products, such as epoxy resins used as coatings on the inside of many food

Absence of bilirubin increases oxidative stress in vivo

Oxidative stress, defined as an imbalance between oxidants and antioxidants in favor of the former, is a hallmark of many diseases, including cardiovascular disease (CVD) and related metabolic syndrome. Modifying uncontrolled oxidative stress may attenuate the development

Capillary number in the “late” pattern correlates with the progression of organ involvement in systemic sclerosis

Systemic Sclerosis (SSc) is an autoimmune rheumatic disease characterized by vascular alterations and tissue fibrosis of multiple organs. Vascular structural alterations are detected early and seem to play an important role in SSc pathogenesis. Microvascular damage is

Non-medicated milk replacer containing Bacillus amyloliquefaciens reduces intestinal pathogenic bacteria counts in dairy calves and adult dogs

Waste milk is not suitable for human intake; however, it contains essential nutrients that can support calf growth. About 22–62 kg of waste milk is wasted per cow yearly in the USA, leading to a drastic economic

Dementia with Lewy bodies and Parkinson’s disease-dementia: Current perspectives

Dementia with Lewy bodies (DLB) and Parkinson’s disease-dementia (PDD) are two closely related major neurocognitive disorders with Lewy bodies of unknown etiology. Both disorders show notable overlap in their clinical presentation, pathological features, biochemistry, and genetic risk

Why do syringe-like nanomachines work efficiently?

Cells of living organisms widely use biological nanomachines: complex or simple systems with size less than ten millionth of a meter. Nanomachines are also used by viruses, which are the form of life that are unable to

Symmetry makes electrons disperse peculiarly

Electronic dispersion is dependence of electron’s total energy on its momentum. This notion is so important for physical properties of materials, that each form of dispersion has its own name. Until recently only three sorts of dispersions

31st American Psychiatry, Psychology and Nursing Congress. Chicago, USA. March 18-19, 2019

We are delightful to welcome you to the 31st American Psychiatry, Psychology and Nursing Congress which is scheduled in the month of March 18-19, 2019 at Chicago, USA organized by Conference Series LLC Ltd in collaboration with

How exercise can improve your mental health – it’s a no brainer!

A plethora of studies are emerging which show the positive effects that exercise can have on mental health and emotional state. The physical effects of exercise include reduction of blood pressure, greater cardiovascular fitness, weight loss and

The cardioprotective effects of (-)-Epicatechin are mediated through arginase activity inhibition in a murine model of ischemia/reperfusion

Cardiovascular diseases including acute myocardial infarction (AMI), are the leading cause of death worldwide. Current treatment for AMI caused by a coronary artery occlusion is the restoration of blood flow (i.e., reperfusion) by angioplasty (percutaneous coronary intervention)

The NO-heme signaling hypothesis

The importance of the NO-synthase(NOS)/soluble guanylyl cyclase (sGC) signaling for health and disease is undisputable (Nobel Prize in Biology and Medicine, 1998). Many studies demonstrated that this pathway is critically implicated in the regulation of cardiovascular, nervous,

Not only pasta: using durum wheat semolina for producing high quality Dittaino bread

Artisanal agri-food products are obtained according to traditional recipes and processing technologies, with features of high quality and genuineness. The “protected designation of origin” (PDO) quality mark identifies a food product whose features strictly depend on the

A new strategy to deliver anti-cancer nanodrugs and decrease their toxic side effects by temporarily blunting the RES uptake using Intralipid®

Nanodrugs, or nanotechnology-based therapeutics, show great promise for treating a number of diseases, including cancer. However, an analysis of the literature from the past 10 years finds that in studies of cancer nanodrugs, a very small fraction