Tag Archives:mtDNA

Sequencing of mtDNA of multiple single mitochondrion isolated from live cells identifies common heteroplasmic sites

Mitochondria are organelles present in all eukaryotic cells, including brain cells, and supply ATP required for cellular physiology through a series of redox reactions known as oxidative phosphorylation. They are unique in their requirement for expression of

‘DNA Fossils’, ancient mtDNA preserved in the nuclear genome: witnesses of human evolution milestones

线粒体DNA片段(mtDNA)are known to get inserted into the DNA of the cell nucleus (i.e., our main genome) and to form NUMTs, i.e. dysfunctional sequences, nuclear pseudogenes of the mtDNA. Hundreds of NUMTs have