Tag Archives:histone variants

Preparation of various nucleosomes for biochemical and structural analyses

Preparation of various nucleosomes for biochemical. AoS

Genomic DNA, which encodes genetic information, is three-dimensionally organized in the cell as chromatin. Its basic unit is the nucleosome, a disc-like structure containing two copies each of histones H2A, H2B, H3, and H4, with DNA wound around