Tag Archives:zika

A vaccine candidate for Zika with potential for reduced risk of antibody-dependent enhancement (ADE)

Zika virus (ZIKV) is a mosquito-borne flavivirus that has rapidly extended its geographic range. Its association with abnormal fetal brain development, sexual transmission, and lack of a preventive vaccine have constituted a global health concern. Designing a

How to use machine learning to discover relevant aspects in the Dengue Virus protease and guide the drug discovery process?

Dengue Virus (DENV) is perhaps one of the most relevant viral pathogens in tropical and sub-tropical areas. A World Health Organization (WHO) report indicates that DENV related infections have increased 30-fold in the last 50 years. DENV

What can computational tools tell us about one of the non-structural proteins on Zika virus?

Zika virus has come to global attention even when it only causes mild symptoms to none. Then, why WHO declared a global emergency in 2016? Beside the rapid expansion of the outbreak through Asia and Latin America,

How realistic is the potential global spread of Zika virus and should we all be worried?

Unless you have taken a holiday on Mars for the whole of this year no doubt by now you will have heard of Zika. This is the virus that has emerged in the last 18 months to

Zika virus infection during pregnancy and small heads: What is the connection and what can be seen by imaging

Within the last year, the outbreak of Zika virus infection in Brazil became a “public health emergency of international magnitude and concern”. The global discussions about the risk of Zika virus infection for pregnant women ahead of