Tag Archives:disease models

Reprogramming skin into brain to study aging and age-related brain diseases

AoS. Reprogramming skin into brain to study aging and age-related brain diseases.

“Inevitable as the passing of time” is a common phrase and a simple truth; in our lives, we may have impactful experiences, grow and learn but, inescapably, we age. It is clear that as we age, our

Building an artificial kidney from human stem cells

Building an Artificial Kidney from Human Stem Cells. AoS

Many diseases and drugs affect kidney function by damaging the glomeruli — the major site of blood filtration and a target for many diseases. An in vitro model of the human glomerulus could facilitate therapeutic discovery and

Of flies and men: investigating human disease in fruit flies

My lab studies diseases which affect the neurons connecting our brains to the muscles throughout our bodies, called motor neurons. In particular, we are interested in the hereditary spastic paraplegias (or HSPs for short), a group of