Tag Archives:cancer therapy

A molecular passport authorizes intracellular travel for a potential cancer therapy antibody

AoS. A Molecular Passport Authorizes Intracellular Travel for a Potential Cancer.

Whether from external environmental factors or spontaneous intracellular processes, the DNA in our cells is under constant bombardment by DNA damage. Because unrepaired DNA damage can cause cell death, our cells have evolved vital mechanisms to repair

Allosteric degraders of EGFR leading to cancer cell detachment-promoted death

AoS. Allosteric Degraders of EGFR Leading to Cancer.

Epidermal growth factor receptor (EGFR) allosteric tyrosine kinase inhibitors (TKIs) have emerged as a therapeutic option for overcoming drug resistance in cancer. We have developed furfuryl derivatives of 4-allyl-5-[2-(4-alkoxyphenyl)-quinolin-4-yl]-4H-1,2,4-triazole-3-thiol and have shown that these compounds bind to

Chronic myeloid leukaemia: a success story in cancer therapy

Chronic myeloid leukaemia (CML) is a haematological malignancy caused by a chromosomal translocation that places the c-ABL oncogene, normally located on the long arm of chromosome 9, under the control of the breakpoint control region (BCR) on

2nd Annual Summit on Cell Signaling and Cancer Therapy. Philadelphia, USA. September 19-20, 2018

2nd Annual Summit on Cell Signaling and Cancer Therapy is bustling to be held at Philadelphia, USA during September 19-20, 2018 hosted by Conferences Series. Through the theme “The Scientific Innovations in the field of Cancer Therapy

Lutetium-177 radioisotope targeted therapy for treatment of cancer and other diseases

By their nature, radioactive isotopes are unstable and can change to more stable forms by radioactive decay and emission of different types of radiation. This emitted radiation is useful for cancer treatment which includes placement of “sealed”

Small-molecule RETRA is effective against a fatal childhood cancer

The bone tumor Ewing’s sarcoma is one of the most aggressive cancers in childhood and adolescence. Before the era of chemotherapy, more than 90% of Ewing’s sarcoma patients succumbed to their disease. With the introduction of intensive