Tag Archives:angiogenesis
Lernaean hydra puzzle in compensatory angiogenesis and tumor drug resistance
在我们继续进行之前,应用Lernaean的类比hydra to compensatory angiogenesis and tumor drug resistance against anti-angiogenic drugs (AADs), let us have a cursory look at the interesting mythology of this hydra. According to Greek
Blood vessels regulate fetal brain growth
Millions of neurons are generated during fetal development from progenitor cells that reside inside the embryonic brain. These neural progenitor cell (NPC)s divide many times to generate new neurons in a process termed ‘neurogenesis’. At each cell
A newly identified protein controls endothelial barrier function by acting as a cellular glue
The endothelial barrier function maintains vascular and tissue homeostasis, and therefore modulates many cardinal physiological processes such as angiogenesis, immune responses, and dynamic fluid exchanges throughout organs. Blood vessels rely on endothelial cell-cell adhesion to generate a
Cancer and blood vessels: an old ridlle resolved
As any other organ of the human body, cancer needs a blood supply to provide oxygen and nutrients and to eliminate wastes. Although already the ancient Greeks had realized that there is a close relationship between tumours
Prox-1 and adipogenesis
Adipogenesis is the biological process that controls adipocytes differentiation and is one of the most well studied models of cellular differentiation. Adipose tissue is involved in the control of energy balance and especially in the study of
Heat shock protein as a novel druggable target in angiogenesis?
Angiogenesis is a physiological process that involves formation of new blood vessels from pre-existing vessels for efficiently providing oxygen and nutrients during growth and development, as well as during wound healing. Under pathological conditions, angiogenesis is regulated
Silencing a microRNA may keep the doctor away for diabetic wounds
Patients with diabetes are frequently afflicted with impaired wound healing that may progress into chronic, diabetic ulcers, often leading to complications including limb amputation with increased risk of morbidity and mortality. These ulcers occur not only in
Imaging tumor development using next generation raster scan optoacoustic mesoscopy
Cancer is one of the major diseases in the 21st century. Hundreds of billions of dollars have been spent on cancer research in the last half century, but still, our understanding of the disease mechanisms is limited.
Demyelination and remyelination signalling in multiple sclerosis as an aid to targeted therapy
多发性硬化(MS)是一种炎症autoimmune disease of the central nervous system (CNS) characterised by demyelination. Demyelination, i.e. damage and erosion of the myelin sheath which protects the nerve fibres, occurs in the white matter of
New function for the well-known lipids
Angiogenesis is the new blood vessels formation in adult tissues which share some similarities to growth of blood vessels during development called vasculogenesis. It is estimated that growth of any tissue to the sizes above 2-3 mm3
Metabolism and pheochromocytoma/paraganglioma
Tumors are named according to the organ or the tissue whose cells undergo biological derangement causing the loss of the control mechanisms that normally limit cell growth. Therefore, breast tumors derives from the cells of the ducts of
Topical administration of an antimicrobial peptide as a new strategy for improved burn wound healing
Burn wounds represent a major global concern, as more than 100 million people worldwide are estimated to experience burn injuries every year. These may be caused upon exposure to heat, radiation, chemicals or electric shocks, often resulting
