Daily Archives:January 27, 2017

Cellular migration required for testis development

Gonad development requires the integration of multiple cell types of various origins. Testis development in particular depends on the crucial step of vascular endothelial cell migration from the mesonephros (the embryonic kidney) into the neighboring gonad tissue.

A multistep virtual screening approach to identify proteasome inhibitors

Proteasome plays a fundamental role in the protein turnover by degrading misfolded, abnormal or damaged proteins, previously labeled through addition of a polyubiquitin chain. An aberration of this proteolytic system could result in different types of hematological

Could low albumin be a marker of an undiagnosed cancer?

Cancer is an increasingly common problem that affects one-in-two British people over the course of their lifetime. Survival rates are getting better with increased awareness, better tests and more effective treatments, but the UK still lags behind

How to characterize best the genetic content of small supernumerary marker chromosomes

An inborn genetic defect can be found prenatally or postnatally. The best known and most frequently observed reason for such developmental delay and/or mental retardation is Down-syndrome, also known as trisomy 21. I.e. besides the normally present